| Date | Home | Away | Result |
|---|---|---|---|
| 12/16/25 12:00 PM | SD Eibar | FC Elche | 0-1 |
| 12/16/25 12:00 PM | Deportivo La Coruna | RCD Mallorca | 1-0 |
| 12/16/25 2:00 PM | Sporting Gijon | FC Valencia | 0-2 |
| 12/16/25 2:00 PM | CD Eldense | Real Sociedad | 1-2 |
| 12/16/25 2:30 PM | CD Guadalajara | FC Barcelona | 0-2 |
| 12/17/25 11:00 AM | CyD Leonesa | UD Levante | 1-0 |
| 12/17/25 12:00 PM | Albacete Balompie | Celta Vigo | 5-2a.PSO |
| 12/17/25 12:00 PM | Racing Santander | FC Villarreal | 2-1 |
| 12/17/25 12:00 PM | SD Huesca | CA Osasuna | 2-4a.e.t |
| 12/17/25 12:00 PM | Atletico Baleares | Atletico Madrid | 2-3 |
| 12/17/25 2:00 PM | Deportivo Alaves | FC Sevilla | 1-0 |
| 12/17/25 2:00 PM | CF Talavera de la Reina | Real Madrid | 2-3 |
| 12/18/25 12:00 PM | CF Ourense | Athletic Bilbao | --- |
| 12/18/25 12:00 PM | Burgos CF | FC Getafe | --- |
| 12/18/25 2:00 PM | Real Murcia C. F. | Real Betis Sevilla | --- |
| 1/6/26 12:00 PM | FC Granada | Rayo Vallecano | --- |